Debunking the myths of HPMC adoption

Published: 2-Sep-2025

Adopting new products, formulations and ways of working can be a challenge for industries as regulated as pharmaceuticals, writes Dr Subhashis Chakraborty, General Manager, Head of Global Product Management, at ACG Capsules

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Factors ranging from inertia to fear of failure can dominate conversations on the shop floor and in boardrooms, subsequently hindering plans for innovation and growth 

The adoption of HPMC capsules is a classic example of this reticence.

Despite their growing use in nutraceuticals, their versatility, customisable release profiles, insusceptibility to the dangers of crosslinking and their consumer-friendly traits (vegetarian and biodegradable), there remains a reluctance in the industry to embrace HPMC.

Conversations with many pharmaceutical manufacturers suggest that their preference is to stick with gelatin as the status quo … and that the true value and benefits of HPMC are yet to be understood or acted upon within the industry.

To help quell these fears and encourage scientists to add HPMC capsules to their product lines, this article aims to bust some of the most common myths, misconceptions and excuses we’ve heard about HPMC — aiming to highlight the importance of HPMC in the future of capsule technology, drug delivery and, ultimately, patient care. 

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