Lubrizol will showcase the benefits of its polymer-based excipients for the solubility, bioavailability and palatability of APIs and nutraceuticals at CPHI Frankfurt (28–30 October 2025/Stand 8.0M71).
The company’s best-in-class solutions highlighted at CPHI will include the following.
Apisolex polymer excipient
As the number of poorly soluble APIs grows, many existing excipients are unable to solve all of the complex challenges facing formulators.
Apisolex is a polyamino acid-based polymer excipient for injectable and parenteral drug formulations with the potential to create life-changing therapies.
With other benefits, including high drug loading and simple formulation, it can enhance the solubility of APIs 50,000-fold.
Apinovex polymer excipient is designed to enhance the solubility of BCS Class II and IV APIs for the development of more efficient oral dosage forms. Benefits include
- up to 10x improvement in the dissolution of crystalline APIs
- high drug loading (up to 80%) via spray drying, enabling smaller tablet and capsule sizes
- stable amorphous solid dispersions, even after 6 months under accelerated conditions
- potential to create innovative oral formats, such as custom release profiles and multiple APIs in one tablet.
Carbopol polymer excipient
Suitable for a range of formulations, including topical and oral applications, Carbopol polymer excipient has been used by the pharmaceutical and nutraceutical industries for more than six decades. Its benefits include
- improved delivery of active ingredients in oral drug formulations
- excellent physical properties for tablet hardness and lower friability
- enhanced texture and stability, making them suitable for creams, lotions and gels
- taste-masking and high drug-loading, enabling palatable and easier formulations (especially for paediatric and geriatric consumers).
Carbopol polymer excipient is also ideal for supplement applications such as tablets, capsules, gummies and chewables, for which its benefits include
- enhancing bioavailability, stability, taste and texture
- enabling ingredients to be dispersible in liquid forms
- limiting the interaction of ingredients with other components (such as iron and vitamin C).
Additionally, Lubrizol offers expertise and capabilities to help companies accelerate their innovations to market.