Latest Media

New White Paper demonstrates value of integrating FlowIR data with Vapourtec Flow Commander software

Gives two examples where FlowIR was used as the key inline diagnostic tool to optimise reaction times

Don’t be thrown off balance – safer operations in biofermentation

Achieving high biofermentation API yield in the minimal time necessitates careful, continuous control of a number of state parameters. Mistakes in process management can result in reduced productivity, extended runs, and in the worst cases, loss of an entire batch. This white paper shows how recent developments in process analytics go a long way to simplifying sensor operations and minimising the risk of human error.

New miniature valves reduce energy consumption by 75%

Reducing the energy consumption of small solenoid valves may not seem particularly significant in isolation, but the knock-on benefits of Bürkert’s TwinPower valves can make a surprisingly large contribution to improving sustainability of labs

On-line TOC and ozone measurement for pharmaceutical waters

The quality of pharmaceutical waters used in product manufacturing must meet all International Pharmacopeia regulations. Any out-of-specified conditions must be identified and corrected immediately

Burkert universal control head delivers cost savings through standardisation

Burkert\'s new Type 8681 control head is ideal for applications on valves used in the hygienic processing industries, where it cuts costs for users by virtue of its ability to be fitted to any manufacturer\'s valves. It has a range of adapters that allows it to be fitted to any actuator currently on the market. It also offers the advantages of easy installation and checking.

Derived measurements for Peak TOC and Average TOC

Compendial Pharmaceutical Waters such as Purified Water and Water for Injection are commonly produced and used continuously as part of the pharmaceutical manufacturing process. Because of this process of continuous usage, demonstration of compliance with TOC regulatory requirements and Pharmacopeia guidelines can become challenging

Optimising enzymatic catalysis with <i>in situ</i> reaction analysis

Monitoring reaction process reduces costs and enhances safety, new White Paper shows

New White Paper sheds light on strengths of flow chemistry

Revolutionary role includes ability to enhance product quality, increase yield, elucidate synthetic route and improve reaction safety, all while reducing cycle time

Retrofit solution to an expensive conundrum

Bespoke retrofit systems are a cost-effective alternative to upgrading tablet and capsule machinery to cope with higher potency APIs, says PSL

Laetus helps Lilly get a jump on the regulation

On 1 January 2011, the nine packaging lines of the Fegersheim Lilly site had to be ready to comply with the new regulation on the move to the CIP 13 and the DataMatrix code

Valve innovation optimises pharmaceutical processes

Paul Trevitt, General Manager, Burkert Fluid Control Systems, discusses how Robolux valves can remove dead legs, minimise hold-up volumes and reduce process times

Optical oxygen systems with ISM – a powerful combination

Open the way for enhanced process control in biotech applications

New experimental techniques for organic synthesis

Chemical synthesis beyond the round bottom flask - a review of modern technologies

Choosing the optimum flowmeter

Choosing the right flowmeter from the dozens of types available is difficult. Paul Trevitt, of Burkert UK, provides a few insights

Customised valve solutions revolutionise steam sterilisation

Steam sterilisation of medical instruments requires a total evacuation of air from the chamber. Bürkert has developed a compact system solution based on an innovative multi-functional block design

Challenges of modern distribution

Distributors of chemicals are having to take increasing responsibility for areas such as supply chain security, quality of materials, ethical sourcing of products and keeping both themselves and their customer up to date with the latest regulations, including REACH and the recent Classification Labelling and Packaging legislation

Production of pharmaceutical compounds through microbial fermentation

Most people’s experience of fermentation will be through its most famous and popular use – the brewing of beer

Filtration trials with SAFC EX-CELL CD Hydrolysate Fusion

Following the launch of the EX-CELL CD Hydrolysate Fusion – the first fully chemically defined media supplement of its kind in the industry – SAFC conducted a study with partner company Sartorius Stedim Biotech to determine the throughput and biological activity of filters

Fermentation technology: cooking up new therapeutics

With a new state-of-the-art, cGMP fermentation facility in Jerusalem, SAFC is looking at new applications for what is viewed by many as a traditional technology. These applications include the synthesis of High Potency Active Pharmaceutical Ingredients (HPAPIs) and therapeutic drugs

Trends in the manufacturing of viral gene therapeutics and next generation vaccines

Gene therapy is still an experimental technology, but the dangers are now much better understood, according to Jeff Strobel, site director, SAFC Carlsbad, CA

Handling protocols: key consideration in HPAPI market

Over the past 10 years, the manufacture of highly potent APIs has become increasingly attractive to contract manufacturers, says Trevor Calkins, director of process development, SAFC

Linking biological molecules to highly potent APIs

Antibody-drug conjugate technology is the ‘smart bomb’ in the arsenal of weapons used to target cancer cells, says Cynthia Wooge, SAFC process development manager

IR spectroscopy on the move

Perkin Elmer\'s latest spectrometer, Spectrum Two, brings spectroscopy to the non-specialist

Temperature tracking

As clinical trial sites move to distant geographic areas and more biologics are involved, temperature monitoring of drug shipments becomes a growing need. Almac has responded with a system it believes will transform temperature monitoring for clinical trials

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  3. On-line TOC and ozone measurement for pharmaceutical waters The quality of pharmaceutical waters used in product manufacturing must meet all International Pharmacopeia regulations. Any out-of-specified conditions must be identified and corrected immediately
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